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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinoblastoma (RB)
ncRNA name hsa-miR-145
ncRNA Category miRNA
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line RB cell lines Y79, Weri-Rb1 and SO-RB50
Methods qPCR,transfection, luciferase reporter assay, MTT assay, migration and invasion assay, Western blot
Expression pattern down-regulated
Functional description miR-145 functions as a tumor suppressor in RB by directly targeting ADAM19.
PubMed ID 26823772
Year 2015
Title MiR-145 suppressed human retinoblastoma cell proliferation and invasion by targeting ADAM19.
Drug-related ncRNA NO

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